1 Microbial Perspectives in the Twenty-First Century 1

William Wade

2 Diagnosis, Epidemiology, and Global Impact of Endodontic Infections 11

Dag Ørstavik

3 Microbiology of Dental Caries and Dentinal Tubule Infection 25

Robert M. Love and Anne C.R. Tanner

4 Culture-Based Analysis of Endodontic Infections 51

Gunnar Dahlén

5 Molecular Analysis of Endodontic Infections 81

José F. Siqueira, Jr, and Isabela N. Rôças

6 Extraradicular Endodontic Infections 129

Brenda P. F. A. Gomes and Ericka T. Pinheiro

7 Virulence of Endodontic Bacterial Pathogens 149

Christine Sedgley

8 Viruses in Endodontic Pathosis 179

Mohamed Sabeti

9 Fungi in Endodontic Infections 197

Bilge Hakan Sen and B. Güniz Baksi

10 Severe Head and Neck Infections 231

Jaime S. Brahim and Robert A. Ord

11 Endodontic Infections and Pain 251

Anibal Diogenes and Ken M. Hargreaves

12 Systemic Antibiotics in Endodontic Infections 269

Ashraf F. Fouad

13 Topical Antimicrobials in Endodontics 287

Anil Kishen

14 Endodontic Infections in Incompletely Developed Teeth 311

George T.J. Huang, Domenico Ricucci, and Louis M. Lin

15 Prognosis of Healing in Treated Teeth with Endodontic Infections 341

Shimon Friedman

16 Endodontic Infections and Systemic Disease 385

Ashraf F. Fouad